Article
Searching for an immunogenetic factor that will illuminate susceptibility to non-tuberculous mycobacterial disease.
Human immunology - 1 Oct 2013
Affandi Jacquita S, Hendry Shona, Waterer Grant, Thomson Rachel, Wallace Hilary, Burrows Sally, Price Patricia
Abstract excerpt
The incidence of pulmonary non-tuberculous mycobacteria (NTM) disease in otherwise healthy adults is increasing as the population ages. The organisms are ubiquitous so susceptibility probably reflects a deficiency in a protective immune response. Here we investigate if singlenucleotide polymorphisms (SNP) affecting cytokines, chemokines and their receptors associate with pulmonary NTM disease. Samples from NTM...
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