Article
Association of tumor necrosis factor-alpha and interferon gamma gene polymorphisms and their plasma levels in leprosy, HIV and other peripheral neuropathies.
Cytokine - 1 Dec 2015
Sykam Aparna, Gutlapalli V R, Tenali Sandeep P, Meena A K, Chandran Priscilla, Pratap D V S, Suneetha Sujai, Suneetha Lavanya M
Abstract excerpt
OBJECTIVE: Mycobacterium leprae and Human Immunodeficiency Virus (HIV) are causative agents known to be involved in nerve damage in leprosy and HIV-peripheral neuropathy (HIV-PN) respectively. Among other peripheral neuropathies the most common is diabetic neuropathy, which is metabolically induced. The proinflammatory cytokines TNF-α and IFN-γ have been implicated in the pathogenesis of peripheral neuropathy....
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