Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Host Genetic Variation Impacts SARS-CoV-2 Vaccination Response in the Diversity Outbred Mouse Population

20 Jan 2024

Abstract excerpt

The COVID-19 pandemic led to the rapid and worldwide development of highly effective vaccines against SARS-CoV-2. However, there is significant individual-to-individual variation in vaccine efficacy due to factors including viral variants, host age, immune status, environmental and host genetic factors. Understanding those determinants driving this variation may inform the development of more broadly protective...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to SARS-CoV-2 and COVID-19 Research
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38276675
DOI: 10.3390/vaccines12010103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Host Genetic Variation Impacts SARS-CoV-2 Vaccination Response in the Diversity Outbred Mouse PopulationPMID 38276675Read ↗

The Diversity Outbred Mouse Population Is an Improved Animal Model of Vaccination against Tuberculosis That Reflects Heterogeneity of Protection.Semantic proximity Read ↗

Tuberculosis susceptibility and vaccine protection are independently controlled by host genotypeSemantic proximity Read ↗

Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype.Semantic proximity Read ↗

Characterization of Collaborative Cross mouse founder strain CAST/EiJ as a novel model for lethal COVID-19Semantic proximity Read ↗

Host genetic background is a barrier to broadly effective vaccine protection: Relevance to BCG and <i>Mycobacterium tuberculosis</i> InfectionSemantic proximity Read ↗

Characterization of Collaborative Cross mouse founder strain CAST/EiJ as a novel model for lethal COVID-19Semantic proximity Read ↗

Host genetic background is a barrier to broadly effective vaccine–mediated protection against tuberculosisSemantic proximity Read ↗

Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection in Collaborative Cross mice.Semantic proximity Read ↗

Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative CrossSemantic proximity Read ↗

Genetic diversity in the collaborative cross model recapitulates human West Nile virus disease outcomes.Semantic proximity Read ↗

Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross.Semantic proximity Read ↗

Multiple genetic loci influence vaccine-induced protection against Mycobacterium tuberculosis in genetically diverse miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.