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Article

CDKN2A/B deletion in IDH-mutant astrocytomas: An evaluation by Fluorescence in-situ hybridization.

Journal of neuro-oncology - 1 Mar 2024

Ranade Manali, Epari Sridhar, Shetty Omshree, Dhanavade Sandeep, Chavan Sheetal, Sahay Ayushi, Sahu Arpita, Shetty Prakash, Moiyadi Aliasgar, Singh Vikash, Dasgupta Archya, Chatterjee Abhishek, Kannan Sadhana, Gupta Tejpal

Abstract excerpt

INTRODUCTION: CDKN2A/B homozygous deletion is one of the defining features of grade 4 in IDH-mutant astrocytic tumours. AIM: To evaluate CDKN2A/B-deletion in IDH-mutant astrocytic tumours and its clinicopathological impact. MATERIALS AND METHODS: CDKN2A/B-deletion was evaluated by Fluorescence in-situ hybridisation (FISH) and interpreted by two recently accepted methods. RESULTS: Eighty-three out of 94 cases...

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Identifiers

PMID: 38265748
DOI: 10.1007/s11060-024-04569-7
PMCID: PMC13287209

Genes

CDKN2A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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