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Translatability of mouse muscle-aging for humans: the role of sex

24 Jan 2024

Abstract excerpt

Muscle-aging drives sarcopenia and is a major public health issue. Mice are frequently used as a model for human muscle-aging, however, research investigating their translational value is limited. In addition, mechanisms underlying muscle-aging may have sex-specific features in humans, but it is not yet assessed whether these are recapitulated in mice. Here, we studied the effects of aging on a functional,...

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PMID: 38265577
DOI: 10.1007/s11357-024-01082-7

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