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Transcriptomic analysis of aging mouse sciatic nerve reveals early pathways leading to sarcopenia

2022-02-03

Abstract excerpt

<h4>Background</h4> Sarcopenia, the age-associated decline in skeletal muscle mass and strength, has long been considered a disease of muscle only, but accumulating evidence suggests that sarcopenia could originate from the neural components controlling muscles. To identify early molecular changes in the efferent nerves that may drive sarcopenia initiation, we performed a longitudinal transcriptomic analysis of t...

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Literature Corpus work
43282c4a-337e-580b-b645-7115882439c8
DOI
10.1101/2022.02.01.478571
Open publication

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Transcriptomic analysis of aging mouse sciatic nerve reveals early pathways leading to sarcopeniaDOI 10.1101/2022.02.01.478571
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