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Article

Conserved and species-specific molecular denominators in mammalian skeletal muscle aging

2 May 2017

Abstract excerpt

Aging is a complex phenomenon involving functional decline in multiple physiological systems. We undertook a comparative analysis of skeletal muscle from four different species, i.e. mice, rats, rhesus monkeys, and humans, at three different representative stages during their lifespan (young, middle, and old) to identify pathways that modulate function and healthspan. Gene expression profiling and computational...

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PMID: 28649426
DOI: 10.1038/s41514-017-0009-8

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