Article
From Churchill to Elephants: The Role of Protective Genes against Cancer.
Genes - 18 Jan 2024
Gazzellone Annalisa, Sangiorgi Eugenio
Abstract excerpt
Richard Peto's paradox, first described in 1975 from an epidemiological perspective, established an inverse correlation between the probability of developing cancer in multicellular organisms and the number of cells. Larger animals exhibit fewer tumors compared to smaller ones, though exceptions exist. Mice are more susceptible to cancer than humans, while elephants and whales demonstrate significantly lower...
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