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Article

Mechanisms of cancer resistance in long-lived mammals.

Nature reviews. Cancer - 1 Jul 2018

Seluanov Andrei, Gladyshev Vadim N, Vijg Jan, Gorbunova Vera

Abstract excerpt

Cancer researchers have traditionally used the mouse and the rat as staple model organisms. These animals are very short-lived, reproduce rapidly and are highly prone to cancer. They have been very useful for modelling some human cancer types and testing experimental treatments; however, these cancer-prone species offer little for understanding the mechanisms of cancer resistance. Recent technological advances...

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PMID: 29622806
DOI: 10.1038/s41568-018-0004-9
PMCID: PMC6015544

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