Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Preventive Evolutionary Medicine of Cancers

5 Dec 2012

Abstract excerpt

Evolutionary theory predicts that once an individual reaches an age of sufficiently low Darwinian fitness, (s)he will have reduced chances of keeping cancerous lesions in check. While we clearly need to better understand the emergence of precursor states and early malignancies as well as their mitigation by the microenvironment and tissue architecture, we argue that lifestyle changes and preventive therapies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA gene mutations in cancer
Share to Cancer Genomics and Diagnostics
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23396860
DOI: 10.1111/eva.12033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Preventive Evolutionary Medicine of CancersPMID 23396860Read ↗

The guardians of inherited oncogenic vulnerabilities.Semantic proximity Read ↗

The sculpting of somatic mutational landscapes by evolutionary forces and their impacts on aging-related disease.Semantic proximity Read ↗

Cancer as a disease of old age: changing mutational and microenvironmental landscapes.Semantic proximity Read ↗

Toward an evolutionary model of cancer: Considering the mechanisms that govern the fate of somatic mutations.Semantic proximity Read ↗

Cancer evolution: from Darwin to the Extended Evolutionary SynthesisSemantic proximity Read ↗

Defeating lethal cancer: Interrupting the ecologic and evolutionary basis of death from malignancy.Semantic proximity Read ↗

Changing mutational and adaptive landscapes and the genesis of cancer.Semantic proximity Read ↗

The Hallmarks of Cancer as Eco-Evolutionary ProcessesSemantic proximity Read ↗

Cancer Evolution and the Limits of Predictability in Precision Cancer MedicineSemantic proximity Read ↗

Clonal Evolution in Healthy and Premalignant Tissues: Implications for Early Cancer Interception Strategies.Semantic proximity Read ↗

Evolutionary dynamics of cancer prevention.Semantic proximity Read ↗

Interpreting cancer genetics through a two-step "evolutionary cascade hypothesis": bridging neutral and selective perspectives.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.