Article

Cancer Prevalence Across Vertebrates

2023-02-16

Abstract excerpt

Cancer is pervasive across multicellular species, but what explains differences in cancer prevalence across species? Using 16,049 necropsy records for 292 species spanning three clades (amphibians, sauropsids and mammals) we found that neoplasia and malignancy prevalence increases with adult weight (contrary to Peto’s Paradox) and somatic mutation rate, but decreases with gestation time. Evolution of cancer suscep...

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Literature Corpus work: 0e624093-e358-530a-add6-55aef6066fa6
DOI: 10.1101/2023.02.15.527881

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