Article
Advanced insights on tumor-associated macrophages revealed by single-cell RNA sequencing: The intratumor heterogeneity, functional phenotypes, and cellular interactions.
Cancer letters - 1 Mar 2024
Yang Sen, Wang Mengyi, Hua Yuze, Li Jiayi, Zheng Huaijin, Cui Ming, Huang Nan, Liu Qiaofei, Liao Quan
Abstract excerpt
Single-cell RNA sequencing (scRNA-seq) is an emerging technology used for cellular transcriptome analysis. The application of scRNA-seq has led to profoundly advanced oncology research, continuously optimizing novel therapeutic strategies. Intratumor heterogeneity extensively consists of all tumor components, contributing to different tumor behaviors and treatment responses. Tumor-associated macrophages (TAMs),...
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