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Ovarian cancer‐specific dysregulated genes with prognostic significance: scRNA‐Seq with bulk RNA‐Seq data and experimental validation

5 Mar 2022

Abstract excerpt

A major cause of gynecological cancer -related deaths worldwide, ovarian cancer is characterized by heterogeneity in both tumor cells and the tumor microenvironment (TME). Our study aimed to characterize tumor cell heterogeneity and the infiltration of M2 tumor-associated macrophages (TAMs) in the ovarian cancer TME by single-cell RNA-Seq (scRNA-Seq) analysis combined with bulk RNA sequencing (bulk RNA-Seq)....

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PMID: 35247207
DOI: 10.1111/nyas.14748

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