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Defining and targeting macrophage heterogeneity in the mammary gland and breast cancer

1 Feb 2024

Abstract excerpt

INTRODUCTION: Macrophages are innate immune cells that are associated with extensive phenotypic and functional plasticity and contribute to normal development, tissue homeostasis, and diseases such as cancer. In this review, we discuss the heterogeneity of tissue resident macrophages in the normal mammary gland and tumor-associated macrophages in breast cancer. Tissue resident macrophages are required for mammary...

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PMID: 38426622
DOI: 10.1002/cam4.7053

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