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Article

Advances in single-cell RNA sequencing and its applications in cancer research.

Journal of hematology & oncology - 24 Aug 2023

Huang Dezhi, Ma Naya, Li Xinlei, Gou Yang, Duan Yishuo, Liu Bangdong, Xia Jing, Zhao Xianlan, Wang Xiaoqi, Li Qiong, Rao Jun, Zhang Xi

Abstract excerpt

Cancers are a group of heterogeneous diseases characterized by the acquisition of functional capabilities during the transition from a normal to a neoplastic state. Powerful experimental and computational tools can be applied to elucidate the mechanisms of occurrence, progression, metastasis, and drug resistance; however, challenges remain. Bulk RNA sequencing techniques only reflect the average gene expression...

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Identifiers

PMID: 37612741
DOI: 10.1186/s13045-023-01494-6
PMCID: PMC10463514

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