Article
The role of IL10 and IL17 gene polymorphisms in treatment response in children and adolescents with severe asthma.
Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia - 1 Jan 2024
Vieira Mariana Isadora Ribeiro, Queiroz Mônica Versiani Nunes Pinheiro de, Santana Maria Borges Rabelo de, Silva Hatilla Dos Santos, Oliveira Almirane, Figueiredo Camila Alexandrina Viana, Santos Eduardo Martín Tarazona, Costa Ryan Dos Santos, Lasmar Laura Maria de Lima Belizário Facury
Abstract excerpt
OBJECTIVE: To determine whether polymorphisms of the IL10 and IL17 genes are associated with severe asthma control and bronchodilator reversibility in children and adolescents with severe asthma. METHODS: This was a cross-sectional study, nested within a prospective cohort study of patients with severe asthma. Two outcomes were evaluated: asthma control and bronchodilator reversibility. We extracted DNA from...
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