Article
Association between interleukin-10 polymorphisms and CD4+CD25+FOXP3+ T cells in asthmatic children.
Jornal de pediatria - 1 Jan 2000
Mocellin Magáli, de Azeredo Leitão Lidiane Alves, de Araújo Patrícia Dias, Jones Marcus Herbert, Stein Renato Tetelbom, Pitrez Paulo Márcio, de Souza Ana Paula Duarte, Pinto Leonardo Araújo
Abstract excerpt
OBJECTIVE: The aim of this study was to evaluate the association between possible functional interleukin-10 (IL-10) polymorphisms, IL-10 expression and regulatory T cells (Tregs) frequency, and/or asthma severity in a sample of children and adolescents. METHODS: This is a nested case-control genetic association study. The study sample consisted of children and adolescents aged 8-14 from public schools. Four...
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