Article
IL10 gene polymorphisms are associated with asthma phenotypes in children.
Genetic epidemiology - 1 Feb 2004
Lyon Helen, Lange Christoph, Lake Stephen, Silverman Edwin K, Randolph Adrienne G, Kwiatkowski David, Raby Benjamin A, Lazarus Ross, Weiland Katy M, Laird Nan, Weiss Scott T
Abstract excerpt
IL10 is an anti-inflammatory cytokine that has been found to have lower production in macrophages and mononuclear cells from asthmatics. Since reduced IL10 levels may influence the severity of asthma phenotypes, we examined IL10 single-nucleotide polymorphisms (SNPs) for association with asthma s...
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