Article
The polymorphisms of interleukin 17A (IL17A) gene and its association with pediatric asthma in Taiwanese population.
Allergy - 1 Jul 2009
Wang J Y, Shyur S D, Wang W H, Liou Y H, Lin C G J, Wu Y J, Wu L S H
Abstract excerpt
BACKGROUND: The interleukin 17A (IL17A) gene, located on chromosome 6p and linked to asthma phenotype, is a highly potential candidate gene conferring asthma susceptibility. The purpose of this study was to investigate the genetic association between single nucleotide polymorphisms (SNPs) of IL17A and asthma in Taiwanese children. METHODS: We selected and performed genotyping on nine SNPs that encompass the...
Topics
- Adolescent
- Asthma
- Child
- Child, Preschool
- Female
- Genetic Predisposition to Disease
- Humans
- Interleukin-17
- Linkage Disequilibrium
- Logistic Models
- Male
- Polymorphism, Single Nucleotide