Article
Genetic variation in uncontrolled childhood asthma despite ICS treatment.
The pharmacogenomics journal - 1 Apr 2016
Leusink M, Vijverberg S J H, Koenderman L, Raaijmakers J A M, de Jongste J C, Sterk P J, Duiverman E J, Onland-Moret N C, Postma D S, de Boer A, de Bakker P I W, Koppelman G H, Maitland-van der Zee A H
Abstract excerpt
Genetic variation may partly explain asthma treatment response heterogeneity. We aimed to identify common and rare genetic variants associated with asthma that was not well controlled despite inhaled corticosteroid (ICS) treatment. Data of 110 children was collected in the Children Asthma Therapy Optimal trial. Associations of genetic variation with measures of lung function (FEV1%pred), airway...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.