Article

<em>IL4</em> Gene Variants rs2243250 and rs2243248 and Their Association with Clinical Phenotypes of Severe Asthma in the Mexican Population: In Silico Functional Analysis and Regulatory Implications

2026-05-08

Abstract excerpt

Severe asthma (SA) is a chronic respiratory disease characterized by clinical heterogeneity and poor therapeutic response. Variants in the IL4 gene, including rs2243250 and rs2243248, have been associated with asthma susceptibility and severity in different populations; however, their role in the Mexican population remains unclear. This study evaluated the association of IL4 promoter variants rs2243250 and rs22432...

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Literature Corpus work: 25f8fa47-d13d-565c-a7ac-9d4034092536
DOI: 10.20944/preprints202605.0258.v1

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