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Article

Opsin is present as dimers in COS1 cells: identification of amino acids at the dimeric interface.

Proceedings of the National Academy of Sciences of the United States of America - 28 Feb 2006

Kota Parvathi, Reeves Philip J, Rajbhandary Uttam L, Khorana H Gobind

Abstract excerpt

Rhodopsin in the disk membranes of rod outer segments serves as the dim-light photoreceptor and is a prototypic member of a G protein-coupled receptor family. Electron and atomic-force microscopy indicate that rhodopsin is present as dimers in the native membranes. Here, we have expressed the protein, opsin, in COS1 cells and have studied its molecular state by using FRET and by intermolecular cross-linking after...

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Identifiers

PMID: 16492774
DOI: 10.1073/pnas.0510982103
PMCID: PMC1413904

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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