Article
A user's guide to channelrhodopsin variants: features, limitations and future developments.
Experimental physiology - 1 Jan 2011
Lin John Y
Abstract excerpt
Channelrhodopsins (ChRs) are light-activated channels from algae that provide these organisms with fast sensors to visible light for phototaxis. Since its discovery, channelrhodopsin-2 (ChR2) has been used as a research tool to depolarize membranes of excitable cells with light. Subsequent chimeragenesis, mutagenesis and bioinformatic approaches have introduced additional ChR variants, such as channelrhodopsin-2...
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