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Article

Spatial Intensity Distribution Analysis Reveals Abnormal Oligomerization of Proteins in Single Cells.

Biophysical journal - 18 Aug 2015

Godin Antoine G, Rappaz Benjamin, Potvin-Trottier Laurent, Kennedy Timothy E, De Koninck Yves, Wiseman Paul W

Abstract excerpt

Knowledge of membrane receptor organization is essential for understanding the initial steps in cell signaling and trafficking mechanisms, but quantitative analysis of receptor interactions at the single-cell level and in different cellular compartments has remained highly challenging. To achieve this, we apply a quantitative image analysis technique-spatial intensity distribution analysis (SpIDA)-that can...

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Identifiers

PMID: 26287623
DOI: 10.1016/j.bpj.2015.06.068
PMCID: PMC4547338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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