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Article

Genetic risk and likelihood of prostate cancer detection on first biopsy by ancestry.

Journal of the National Cancer Institute - 8 May 2024

Lee Kyung Min, Nelson Tyler J, Bryant Alex, Teerlink Craig C, Gulati Roman, Pagadala Meghana S, Tcheandjieu Catherine, Pridgen Kathryn M, DuVall Scott L, Yamoah Kosj, Vassy Jason L, Seibert Tyler M, Hauger Richard L, Rose Brent S, Lynch Julie A

Abstract excerpt

Despite differences in prostate cancer risk across ancestry groups, relative performance of prostate cancer genetic risks scores (GRS) for positive biopsy prediction in different ancestry groups is unknown. This cross-sectional retrospective analysis examines the association between a polygenic hazard score (PHS290) and risk of prostate cancer diagnosis upon first biopsy in male veterans using 2-sided tests. Our...

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Identifiers

PMID: 38212986
DOI: 10.1093/jnci/djae002
PMCID: PMC11077300

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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