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Increased mutations in lipopolysaccharide biosynthetic genes cause time-dependent development of phage resistance in Salmonella.

Antimicrobial agents and chemotherapy - 7 Feb 2024

Yu Jing, Zhang Haoyu, Ju Zijing, Huang Jiaqi, Lin Cong, Wu Jie, Wu Yingting, Sun Shuhong, Wang Hongning, Hao Guijuan, Zhang Anyun

Abstract excerpt

Understanding how bacteria evolve resistance to phages has implications for phage-based therapies and microbial evolution. In this study, the susceptibility of 335 Salmonella isolates to the wide host range Salmonella phage BPSELC-1 was tested. Potentially significant gene sets that could confer resistance were identified using bioinformatics approaches based on phage susceptibility phenotypes; more than 90...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 38193669
DOI: 10.1128/aac.00594-23
PMCID: PMC10848759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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