Article
Bacteriophage resistance mechanisms in the fish pathogen Flavobacterium psychrophilum: linking genomic mutations to changes in bacterial virulence factors.
Applied and environmental microbiology - 1 Feb 2015
Castillo Daniel, Christiansen Rói Hammershaimb, Dalsgaard Inger, Madsen Lone, Middelboe Mathias
Abstract excerpt
Flavobacterium psychrophilum is an important fish pathogen in salmonid aquaculture worldwide. Due to increased antibiotic resistance, pathogen control using bacteriophages has been explored as a possible alternative treatment. However, the effective use of bacteriophages in pathogen control requires overcoming the selection for phage resistance in the bacterial populations. Here, we analyzed resistance mechanisms...
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