Article
Fitness costs of phage-driven resistance mutations in Salmonella Enteritidis populations.
Journal of virology - 17 Feb 2026
Lv Peilin, Liu Tingting, Yue Siyu, Chen Yu, Wang Yu, Li Zili, Jin Xiue, Li Yue, Wang Xiliang
Abstract excerpt
In the post-antibiotic era, bacteriophages have emerged as viable alternatives for combating antibiotic-resistant infections. Analogous to the emergence of antibiotic resistance, bacteria can also develop resistance to phages, a process often accompanied by a reduction in bacterial fitness. In this study, we investigated the mechanisms behind the development of phage resistance in Salmonella enterica serovar...
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