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Article

Phage receptor specificity drives cross-resistance patterns and governs fitness trade-offs during sequential resistance acquisition in Salmonella.

The ISME journal - 14 Jan 2026

Wu Yingting, Yu Jing, Tao Weilai, Wu Jie, Gan Yumeng, Wang Yuxuan, Zhao Xin, Hao Xiaojing, Zhang Qian, Wang Hongning, Zhang Anyun

Abstract excerpt

Phages infect bacteria by binding to specific surface receptors, driving co-evolution in microbial communities and offering therapeutic potential. However, how receptor specificity shapes the cross-resistance patterns and evolutionary trade-offs during phage-bacteria co-evolution remains unclear. Here, we investigated the genetic basis and fitness trade-offs of phage resistance in Salmonella to phages targeting...

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Share to Bacterial Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41968384
DOI: 10.1093/ismejo/wrag077
PMCID: PMC13196588

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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