Article
Phage-Bacterial Interaction Alters Phenotypes Associated with Virulence in Acinetobacter baumannii.
Viruses - 8 May 2024
Oyejobi Greater Kayode, Zhang Xiaoxu, Xiong Dongyan, Xue Heng, Shi Mengjuan, Yang Hang, Wei Hongping
Abstract excerpt
Bacteriophages exert strong selection on their bacterial hosts to evolve resistance. At the same time, the fitness costs on bacteria following phage resistance may change their virulence, which may affect the therapeutic outcomes of phage therapy. In this study, we set out to assess the costs of phage resistance on the in vitro virulence of priority 1 nosocomial pathogenic bacterium, Acinetobacter baumannii. By...
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