Article

Single-Cell Genetic Architecture Identifies GSTM1 as a Novel Therapeutic Target for Reversing T-Cell Ferroptosis in NSCLC

2026-04-02

Abstract excerpt

<title>Abstract</title> Background Ferroptosis has emerged as a pivotal mechanism in cancer surveillance, particularly in determining the efficacy of immunotherapy. However, the precise genetic switches that regulate ferroptosis sensitivity within specific immune cell lineages remain poorly characterized due to the resolution limits of bulk tissue analysis. Methods To address this, we constructed a high-reso...

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Identifiers and source

Literature Corpus work: 20a84477-ae57-5396-8b07-cde88018bb08
DOI: 10.21203/rs.3.rs-9010841/v1

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