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Article

Quantifying Dynamic Phenotypic Heterogeneity in Resistant Escherichia coli under Translation-Inhibiting Antibiotics.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) - 1 Mar 2024

Zhu Haishuang, Xiong Yixiao, Jiang Zhenlong, Liu Qiong, Wang Jin

Abstract excerpt

Understanding the phenotypic heterogeneity of antibiotic-resistant bacteria following treatment and the transitions between different phenotypes is crucial for developing effective infection control strategies. The study expands upon previous work by explicating chloramphenicol-induced phenotypic heterogeneities in growth rate, gene expression, and morphology of resistant Escherichia coli using time-lapse...

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Identifiers

PMID: 38193201
DOI: 10.1002/advs.202304548
PMCID: PMC10953537

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