Dynamic gene expression and growth underlie cell-to-cell heterogeneity in Escherichia coli stress response.

Abstract excerpt

Cell-to-cell heterogeneity in gene expression and growth can have critical functional consequences, such as determining whether individual bacteria survive or die following stress. Although phenotypic variability is well documented, the dynamics that underlie it are often unknown. This information is important because dramatically different outcomes can arise from gradual versus rapid changes in expression and...

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