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Article

Microscale insights into pneumococcal antibiotic mutant selection windows.

Nature communications - 30 Oct 2015

Sorg Robin A, Veening Jan-Willem

Abstract excerpt

The human pathogen Streptococcus pneumoniae shows alarming rates of antibiotic resistance emergence. The basic requirements for de novo resistance emergence are poorly understood in the pneumococcus. Here we systematically analyse the impact of antibiotics on S. pneumoniae at concentrations that inhibit wild type cells, that is, within the mutant selection window. We identify discrete growth-inhibition profiles...

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Share to Anti-Bacterial Agents
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Share to Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microbial Sensitivity Tests

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Share to Pneumonia and Respiratory Infections

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Identifiers

PMID: 26514094
DOI: 10.1038/ncomms9773
PMCID: PMC4632196

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