Article

From Resistance Genes to Resistance States: A Transcriptomics-Driven Precision Medicine Framework for Antimicrobial Therapy

2025-12-29

Abstract excerpt

Antimicrobial resistance (AMR) is increasingly addressed through genomic approaches that identify resistance genes and mutations. While these methods have improved surveillance and diagnostics, they often fail to explain patient-specific treatment outcomes, as genetically similar pathogens can exhibit markedly different responses to the same antimicrobial therapy. This discrepancy highlights a fundamental limitati...

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Literature Corpus work: fc70fede-03a4-56a1-a1e9-55e53f591527
DOI: 10.20944/preprints202512.2493.v1

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