Article
Clinical-Molecular characteristics and Post-Translational modifications of colorectal cancer in north China: Implications for future targeted therapies.
Gene - 20 Mar 2024
Chi Yajing, Yuan Hongtu, Fan Qing, Wang Zhendan, Niu Zuoxing, Yu Jinming, Yuan Dandan
Abstract excerpt
This study delineated the elucidate molecular changes and their post-translational modifications (PTMs) in heterogenetic colorectal cancer (CRC) for a deeper understanding of the CRC pathophysiology and identifying potential therapeutic targets. In this retrospective study, the profiles of 13 hot spot gene mutations were analyzed and the microsatellite instability (MSI) status was determined.Employing the...
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