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Correlation between NGS panel-based mutation results and clinical information in colorectal cancer patients

1 Apr 2024

Abstract excerpt

Early mutation identification guides patients with colorectal cancer (CRC) toward targeted therapies. In the present study, 414 patients with CRC were enrolled, and amplicon-based targeted next-generation sequencing (NGS) was then performed to detect genomic alterations within the 73 cancer-related genes in the OncoAim panel. The overall mutation rate was 91.5 % (379/414). Gene mutations were detected in 38/73...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38623252
DOI: 10.1016/j.heliyon.2024.e29299

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