Mutation Spectra of Common Cancer-Associated Genes in Different Phenotypes of Colorectal Carcinoma Without Distant Metastasis.

doi:10.1245/s10434-015-4899-z

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Article

Mutation Spectra of Common Cancer-Associated Genes in Different Phenotypes of Colorectal Carcinoma Without Distant Metastasis.

Annals of surgical oncology - 1 Mar 2016

Chang Shih-Ching, Lin Pei-Ching, Lin Jen-Kou, Lin Chien-Hsing, Yang Shung-Haur, Liang Wen-Yi, Chen Wei-Shone, Jiang Jeng-Kai

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is a heterogeneous disease caused by genetic and epigenetic alterations. This study aimed to describe the mutation frequency of 12 genes in different CRC phenotypes. METHODS: Patients who underwent surgery at the Taipei Veterans General Hospital during 2000-201...

Topics

Adenocarcinoma, Mucinous
Adult
Aged
Aged, 80 and over
Biomarkers, Tumor
Colorectal Neoplasms
Female
Follow-Up Studies
Humans
Male
Microsatellite Instability
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Neoplasm Invasiveness

Neoplasm Recurrence, Local

Neoplasm Staging

Phenotype

Prognosis

Source

Open in PubMed

Identifiers

PMID: 26471487
DOI: 10.1245/s10434-015-4899-z

Genes

BRAF
AKT1
KRAS
NRAS
APC
PTEN
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-26471487-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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