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Article

Mutation Spectra of Common Cancer-Associated Genes in Different Phenotypes of Colorectal Carcinoma Without Distant Metastasis.

Annals of surgical oncology - 1 Mar 2016

Chang Shih-Ching, Lin Pei-Ching, Lin Jen-Kou, Lin Chien-Hsing, Yang Shung-Haur, Liang Wen-Yi, Chen Wei-Shone, Jiang Jeng-Kai

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is a heterogeneous disease caused by genetic and epigenetic alterations. This study aimed to describe the mutation frequency of 12 genes in different CRC phenotypes. METHODS: Patients who underwent surgery at the Taipei Veterans General Hospital during 2000-2010 for CRC (n = 1249) were enrolled. The endpoint was overall survival. The prognostic value was determined with the...

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Identifiers

PMID: 26471487
DOI: 10.1245/s10434-015-4899-z

Genes

BRAF
AKT1
KRAS
NRAS
APC
PTEN
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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