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Characterization of Genomic Alterations in Colorectal Liver Metastasis and Their Prognostic Value

4 Jul 2022

Abstract excerpt

Colorectal liver metastases (CRLMs) are clinically heterogeneous lesions with poor prognosis. Genetic alterations play a crucial role in their progression. The traditional Fong clinical risk score (Fong-CRS) is commonly used for risk stratification and prognosis prediction. By identifying the genomic alterations of CRLMs, we aimed to develop a mutation-based gene-signature-based clinical score (mut-CS) system to...

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PMID: 35860598
DOI: 10.3389/fcell.2021.760618

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