Article

Mendelian randomization of dyslipidemia on cognitive impairment among older Americans

2020-10-21

Abstract excerpt

<h4>Background</h4> Altered lipid metabolism may be a risk factor for dementia, and blood cholesterol level has a strong genetic component. We tested the hypothesis that dyslipidemia (either low levels of high-density lipoprotein cholesterol (HDL-C) or high total cholesterol) is associated with cognitive status and domains, and assessed inferred causality using genetic predisposition to dyslipidemia as an instrume...

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Literature Corpus work: b095e83f-2124-5b7f-9943-51246e68ce54
DOI: 10.1101/2020.10.20.20216036

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