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Article

The molecular classification of cancer‐associated fibroblasts on a pan‐cancer single‐cell transcriptional atlas

1 Dec 2023

Abstract excerpt

BACKGROUND: Cancer-associated fibroblasts (CAFs), integral to the tumour microenvironment, are pivotal in cancer progression, exhibiting either pro-tumourigenic or anti-tumourigenic functions. Their inherent phenotypic and functional diversity allows for the subdivision of CAFs into various subpopulations. While several classification systems have been suggested for different cancer types, a unified molecular...

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PMID: 38148640
DOI: 10.1002/ctm2.1516

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