Article
Comprehensive genomic profiling of small bowel adenocarcinoma by tissue and plasma biopsy.
Genomics - 1 Jan 2024
Yu Dan, Wang Jianzheng, Zheng Bo, Yuan Mingming, Gu Dejian, Chen Rongrong, Chen Xiaobing
Abstract excerpt
Small bowel adenocarcinoma (SBA) is a rare and aggressive malignancy with limited treatment options and poor prognosis. The molecular landscape and immunological characteristics of SBA are poorly understood. Here, we performed comprehensive mutation profiling of tissue and plasma biopsies from 143 and 42 patients with SBA. Analysis showed that SBA had a distinct mutation spectrum from left- and right-sided...
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