Article
Genomic profiling of small bowel adenocarcinoma: a pooled analysis from 3 databases.
British journal of cancer - 1 Jul 2024
Aparicio Thomas, Henriques Julie, Svrcek Magali, Zaanan Aziz, Manfredi Sylvain, Casadei-Gardini Andrea, Tougeron David, Gornet Jean-Marc, Jary Marine, Terrebonne Eric, Piessen Guillaume, Afchain Pauline, Lecaille Cédric, Pocard Marc, Lecomte Thierry, Rimini Margherita, Di Fiore Frédéric, Le Brun Ly Valérie, Cascinu Stefano, Vernerey Dewi, Laurent Puig Pierre
Abstract excerpt
BACKGROUND: Small bowel adenocarcinoma is a rare disease. The genomic profiling tumours according to clinical characteristics and its impact on the prognosis remains unclear. METHODS: A pooled analysis of clinical data, genomic profiling and MisMatch Repair (MMR) status from three databases was performed. RESULTS: A total of 188 tumour samples were analysed. A predisposing disease was reported in 22.3%, mainly...
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