Article
Blood-Based Next-Generation Sequencing Analysis of Appendiceal Cancers.
The oncologist - 1 May 2020
Shaib Walid L, Zakka Katerina, Staley Charles, Roberts Ali, Akce Mehmet, Wu Christina, Alese Olatunji B, El-Rayes Bassel F
Abstract excerpt
BACKGROUND: Appendiceal cancers (ACs) are rare. The genomic landscape of ACs has not been well studied. The aim of this study was to confirm the feasibility of next-generation sequencing (NGS) using circulating tumor DNA (ctDNA) in ACs and characterize common genomic alterations. MATERIALS AND METHODS: Molecular alterations in 372 plasma samples from 303 patients with AC using clinical-grade NGS of ctDNA...
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