Article
Novel mutations found in Mycobacterium leprae DNA repair gene nth from central India.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Jun 2024
Sharma Mukul, Dwivedi Purna, Joshi Vandana, Singh Pushpendra
Abstract excerpt
INTRODUCTION: The importance of DNA repair enzymes in maintaining genomic integrity is highlighted by the hypothesis that DNA damage by reactive oxygen/nitrogen species produced inside the host cell is essential for the mutagenesis process. Endonuclease III (Nth), formamidopyrimide (Fpg) and endonuclease VIII (Nei) DNA glycosylases are essential components of the bacterial base excision repair process....
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