Article
Drug resistance in Mycobacterium leprae from patients with leprosy in China.
Clinical and experimental dermatology - 1 Dec 2015
Liu D, Zhang Q, Sun Y, Wang C, Zhang Y, Fu X, Chen M, Zhou G, Yu X, Wang J, Liu H, Zhang F
Abstract excerpt
BACKGROUND: Previous studies of drug resistance have shown that mutations in the drug resistance-determining region (DRDR) in the Folp1, RpoB and GyrA genes of Mycobacterium leprae are responsible for resistance to dapsone, rifampin and ofloxacin, respectively. AIM: To investigate the prevalence of mutations in genes associated with drug resistance in M. leprae isolates from patients with leprosy in Shandong...
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