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Antibody Humanization via Protein Language Model and Neighbor Retrieval

2023-09-06

Abstract excerpt

Antibody (Ab), also known as immunoglobulin (Ig), is an essential macromolecule involved in human immune response and plays an increasingly vital role in drug discovery. However, the development of antibody drugs heavily relies on humanization of murine antibodies, which often necessitates multiple rounds of sequence optimizations through laborious experimental processes. In recent years, the remarkable capabiliti...

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Literature Corpus work
b96a18f0-2c42-5002-8005-0b8c392efa6a
DOI
10.1101/2023.09.04.556278
Open publication

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Antibody Humanization via Protein Language Model and Neighbor RetrievalDOI 10.1101/2023.09.04.556278
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