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Identification of a core EMT signature that separates basal-like breast cancers into partial- and post-EMT subtypes

4 Dec 2023

Abstract excerpt

Epithelial-mesenchymal transition (EMT) is a cellular plasticity program critical for embryonic development and tissue regeneration, and aberrant EMT is associated with disease including cancer. The high degree of plasticity in the mammary epithelium is reflected in extensive heterogeneity among breast cancers. Here, we have analyzed RNA-sequencing data from three different mammary epithelial cell line-derived...

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PMID: 38111531
DOI: 10.3389/fonc.2023.1249895

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