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Breast cancer epithelial-to-mesenchymal transition: examining the functional consequences of plasticity

1 Nov 2011

Abstract excerpt

The epithelial-to-mesenchymal transition (EMT) is a critical developmental process that has recently come to the forefront of cancer biology. In breast carcinomas, acquisition of a mesenchymal-like phenotype that is reminiscent of an EMT, termed oncogenic EMT, is associated with pro-metastatic properties, including increased motility, invasion, anoikis resistance, immunosuppression and cancer stem cell...

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PMID: 22078097
DOI: 10.1186/bcr3037

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