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EMTome: a resource for pan-cancer analysis of epithelial-mesenchymal transition genes and signatures

10 Dec 2020

Abstract excerpt

BACKGROUND: The epithelial-mesenchymal transition (EMT) enables dissociation of tumour cells from the primary tumour mass, invasion through the extracellular matrix, intravasation into blood vessels and colonisation of distant organs. Cells that revert to the epithelial state via the mesenchymal-epithelial transition cause metastases, the primary cause of death in cancer patients. EMT also empowers cancer cells...

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Cancer Cells and Metastasis
Ferroptosis and cancer prognosis
Hippo pathway signaling and YAP/TAZ

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33299129
DOI: 10.1038/s41416-020-01178-9

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